Eastern Cape accommodation is predominantly centred around the region's parks and private reserves where luxury camps and family-friendly lodges provide the base for exceptional malaria-free, Big 5 safaris. Many of the lodges offer babysitters and safari programmes for kids, making for great hassle-free family holidays.

Accommodation in the Eastern Cape is not limited to safari lodges however; comfortable guest houses on the coast at St Francis Bay or Port Elizabeth offer the perfect pre- or post-safari break as well as providing accommodation options for the eastern half of the Garden Route.